Physiologic Basis for Improved Pulmonary Function after Lung Volume Reduction

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Physiologic basis for improved pulmonary function after lung volume reduction.

It is not readily apparent how pulmonary function could be improved by resecting portions of the lung in patients with emphysema. In emphysema, elevation in residual volume relative to total lung capacity reduces forced expiratory volumes, increases inspiratory effort, and impairs inspiratory muscle mechanics. Lung volume reduction surgery (LVRS) better matches the size of the lungs to the size...

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[Lung volume reduction surgery for pulmonary emphysema].

Surgical treatment for pulmonary emphysema has received renewed attention, because many studies have demonstrated improvements in dyspnea and pulmonary function. After lung volume reduction surgery (LVRS) for carefully selected advanced pulmonary emphysema, pulmonary functional impairments, such as expiratory flow limitation, increase in lung volume, decrease in lung elastic recoil, impaired ga...

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Reduction of Pulmonary Function After Surgical Lung Resections of Different Volume

INTRODUCTION In recent years an increasing number of lung resections are being done because of the rising prevalence of lung cancer that occurs mainly in patients with limited lung function, what is caused with common etiologic factor - smoking cigarettes. OBJECTIVE To determine how big the loss of lung function is after surgical resection of lung of different range. METHODS The study was d...

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Sustained improvements in dyspnea and pulmonary function 3 to 5 years after lung volume reduction surgery.

OBJECTIVES To determine long-term survival rates of patients who underwent lung volume reduction surgery (LVRS) for emphysema and the factors associated with longer survival, and to evaluate levels of perceived dyspnea and health-related quality of life (HRQL) after a follow-up period of 3 to 5.5 years. DESIGN Retrospective observational study. SETTING Academic medical center METHODS Tele...

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Small airway morphometry and improvement in pulmonary function after lung volume reduction surgery.

We examined small airway morphometry from resected lung specimens in 25 patients with severe emphysema undergoing lung volume reduction surgery (LVRS) and correlated their pathologic findings to changes in FEV(1) 6 months after LVRS. Patients were classified into two groups: responders had a more than 12% and a more than 200-ml change in FEV(1) at 6 months, and nonresponders had 12% or less and...

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ژورنال

عنوان ژورنال: Proceedings of the American Thoracic Society

سال: 2008

ISSN: 1546-3222

DOI: 10.1513/pats.200708-117et